We are interested in understanding how plants defend themselves against pathogens. We study the HopZ family of type III effector proteins from Pseudomonas syringae and the immune responses they elicit in plant hosts. We use many different techniques to investigate plant immunity, including genetics, molecular biology, biochemistry, cell biology, genomics, high-throughput screens, and next-generation sequencing. Our long-term goals are to understand the molecular mechanisms of plant immunity, and to identify strategies for durable resistance in plants. We are a collaborative group of scientists who are committed to creativity, curiosity and excellence in science, training the next generation of scientists, and fostering a diverse inclusive welcoming environment that values all people.
The Lewis Lab is located at the Plant Gene Expression Center (PGEC) in Albany, California and is part of a unique collaboration between the Agricultural Research Service of the US Department of Agriculture and the Plant and Microbial Biology Department at the University of California, Berkeley.

Ilea passes her qualifying exam and is awarded NSF fellowship!

Ilea successfully passed her qualifying exam and has been awarded the prestigious NSF graduate research fellowship for her doctoral work!

Research Highlight

Phloem blocked by pathogens
Our review on phloem-limited pathogens is available in early view through Molecular Plant Pathology.

Research Highlight

Jana's paper is now out in Plant Direct!

Awards to current, former and visiting members of the lab!

Congratulations to Ilea, Taylor and Alice. Ilea received the Grace Kase fellowship. Taylor received a poster award at ABRCMS, and Alice received a grant to visit our lab.

Undergraduate course in Plant-Microbe Interactions

9 diseases that threaten your favorite foods
From coffee to bananas to grapes to potatoes, many plants are threatened by disease. Learn more about how plants defend themselves and how microbes cause disease. This upper-division undergraduate course (PMB165) is offered in the spring on Tuesdays and Thursdays from 9:30-11am.

We welcome a new rotation student!

Protein structure
Snigdha Chatterjee from Syracuse University, is a new rotating graduate student in the lab.

Research Highlight

Our methods paper on a quantitative high-throughput yeast two-hybrid (QIS-Seq) is now out in Methods in Molecular Biology!

Research Highlight

Recognition of HopZ1a by ZED1 and ZAR1
Maёl, Jana and Karl's paper is now out in Plant Physiology!


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