We are interested in understanding how plants defend themselves against pathogens. We study the HopZ family of type III effector proteins from Pseudomonas syringae and the immune responses they elicit in plant hosts. We use many different techniques to investigate plant immunity, including genetics, molecular biology, biochemistry, cell biology, genomics, high-throughput screens, and next-generation sequencing. Our long-term goals are to understand the molecular mechanisms of plant immunity, and to identify strategies for durable resistance in plants. We are a collaborative group of scientists who are committed to creativity, curiosity and excellence in science, training the next generation of scientists, and fostering a diverse inclusive welcoming environment that values all people.
 
The Lewis Lab is located at the Plant Gene Expression Center (PGEC) in Albany, California and is part of a unique collaboration between the Agricultural Research Service of the US Department of Agriculture and the Plant and Microbial Biology Department at the University of California, Berkeley.
 
 

Congratulations Nate!

Nate successfully passed his qualifying exam!

Research Highlight

Karl's paper on a putative topoisomerase, ZIN1, that promotes bacterial virulence is now out in First Look at Molecular Plant-Microbe Interactions!

Research Highlight

Our manuscript on a new susceptibility hub that is targeted by Pseudomonas syringae effector proteins is now available at Plant Journal!

Research Highlight

Plant Cell & Environment cover
Our manuscript on natural diversity in HopZ1a recognition has been published in Plant Cell & Environment!

Research Highlight

Nature Methods
Ilea's collaborative project with Joe Bondy-Denomy's lab on genome engineering using CRISPR-Cas3 has been published in Nature Methods!

Jenn and Ilea share the lab's research at summer conferences

Plant Biology 2020 Worldwide Summit
Jenn and Ilea presented the lab's research on plant-microbe interactions at the Plant Biology 2020 Worldwide Summit and Psyringae2020.

The Lewis lab and members of the PGEC took part in a workshop on implicit bias!

Bias Busters
As part of our ongoing commitment to DEI, the Lewis lab and members of the PGEC participated in an excellent workshop on implicit bias.

Jenn gave a talk in MPMI's new virtual series on citrus greening work!

Jenn was invited to give a talk in MPMI's new remote talk series on Yuan and Claire's citrus greening work, which was MPMI's Editor's Pick for March.

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