We are interested in understanding how plants defend themselves against pathogens. We study the HopZ family of type III effector proteins from Pseudomonas syringae and the immune responses they elicit in plant hosts. We use many different techniques to investigate plant immunity, including genetics, molecular biology, biochemistry, cell biology, genomics, high-throughput screens, and next-generation sequencing. Our long-term goals are to understand the molecular mechanisms of plant immunity, and to identify strategies for durable resistance in plants.
The Lewis Lab is located at the Plant Gene Expression Center (PGEC) in Albany, California and is part of a unique collaboration between the Agricultural Research Service of the US Department of Agriculture and the Plant and Microbial Biology Department at the University of California, Berkeley.

Research Highlight

The HopZ family of type III secreted effectors has diverse means of suppressing plant immunity.

Season of Changes

The Lewis lab welcomes a new post-doc and says adieu to another member.

Research Highlight

Recognition of effector proteins in resistant hosts leads to robust immunity that prevents bacterial infection.

Lewis Lab Graduate 2014!

Congratulations to Jane Zhou, official UC Berkeley graduate in 2014!

Undergraduate Research Opportunities

Tania Funes presenting her research poster
We are looking for highly motivated undergraduate students interested in pursuing scientific research.
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